Strongly impaired cognitive functions and concentration, lack of abstraction ability Pain in the right armpit (vaccination arm) Undulating body temperature (+-0.5 degrees) Once, at night, after relief of a severe headache Various drugs relieved it for several hours, fluvoxamine was fading it out, but cognitive impairment remained Pulling, left temporal pressure, dragging on the left part of the head (correlated with cognitive impairment during first 7 months) (see figure figure2 2) NSAR, the remainder was resolved by sartans, statinsĬognitive impairment (as if packed in a cocoon) N/A: Not available, NSAR: Non-steroidal anti-rheumatic drugs, QoL: Quality of life, VAS: Visual analog scale, LPCVS: Long post-COVID vaccination syndrome In October 2022, two days of absence of statins induced a feeling as if the head would tear apart yielding to a complete inability to meet daily requirements. The patient is currently still taking drugs. The same applied to the strong skin reaction between the legs. Varying body temperature has been observed already after the second vaccination lasting two to three weeks. The same holds for oral methyl-prednisolone (4mg/d). A later attempt with ibuprofen (2x200mg) caused strong tearing symptoms in the left head. Each treatment initially worsened symptoms followed by temporary relief of the symptoms once the medications were stopped until they reoccurred.įour attempts were made over two months using different NSARs (aspirin 3x300mg for 3.5 days and then another two days naproxen 2圆00mg for 1.5 days ibuprofen 3圆00mg for five days). Nonsteroidal antirheumatic drugs (NSAR) resolved the brain fog/numbness for approximately five days after intake but symptoms reoccurred within one to three days. Symptoms and their intensity were commonly random with a base affectedness. This is especially true in the very first days when the patient primarily required permanent bed rest. Symptoms of LPCVS, their frequency, course, treatment, and outcome.įor symptoms where the onset is unknown, it is likely that more severe symptoms overlapped the recognition or memory of the symptom. Patients with LPCVS should be taken seriously and treated appropriately. Symptomatic treatment can provide some relief. Despite extensive work-up, a clear cause for the long-term neuro-cognitive deficits cannot be identified. In conclusion, LPCVS is a definite complication of anti-SARS-CoV-2 vaccinations and can severely impact the quality of life and lead to disability. Non-steroidal anti-inflammatory drugs, antihistamines, sartans, and statins have occasionally provided temporary relief. Some of the immune parameters were deflected. Cerebral MRI showed non-specific white matter lesions in a frontotemporal distribution. In addition to brief fever, headache, flickering eyes, skin rashes, tiredness, disorientation, dizziness (brain fog), tiredness, impaired thinking and concentration, and emotional disorders occurred as a result. Our patient is a 39-year-old male with a largely uneventful previous history who developed severe adverse reactions immediately after the third dose of the mRNA-1273 (Moderna) vaccine. It persists 11 months after the third mRNA-1273 (Moderna) vaccine dose has not been reported. Long post-COVID vaccination syndrome (LPCVS) is one of them and is often neglected. It is undisputed that anti-SARS-CoV-2 vaccines can have side effects.
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